Anne-Marie Duff will star in a new play by Wonderland writer Beth Steel at the Almeida Theatre.
Duff will lead the cast of The House of Shades, which follows a family over five decades, with further cast members to be announced.
It is directed by Blanche McIntyre, with design by Anna Fleischle.
Costumes are by Fleischle and Liam Bunster, lighting by Richard Howell, sound by Gregory Clarke, movement by Lucy Hind and casting by Annelie Powell.
The production runs from May 18 to June 27, with press night on May 26.