Comedian Zoe Lyons is to star in the European premiere of An Act of God.
The play, by David Javerbaum, has previously run twice on Broadway, starring Sean Hayes and Jim Parsons.
The London production sees Javerbaum rewrite the play for Lyons and a British audience. His original Broadway production was based on a Twitter account he ran, called @TheTweetOfGod.
An Act of God will be directed by Benji Sperring, and will also star Tom Bowen and Matt Tedford.
It runs at the Vaults in Waterloo from November 27 to January 12, with press night on November 29.
The show is produced by James Seabright.