Eva Noblezada and Andre De Shields will star in Hadestown at the National Theatre in London.
They are joining a London cast of the musical, alongside Reeve Carney, who will reprise his role of Orpheus, the part he performed at the Citadel Theatre in Canada.
Amber Gray and Patrick Page will reprise their roles from the original New York workshop of the production as Persephone and Hades.
The musical, which has music, book and lyrics by Anais Mitchell, runs in rep at the Olivier Theatre from November 2 to January 26. Press night is on November 13.
It will then transfer to Broadway in 2019.
Joining the cast Rosie Fletcher, Carly Mercedes Dyer, Gloria Onitiri, Sharif Afifi and Beth Hinton-Lever.
Completing the cast are Seyi Omooba, Aiesha Pease, Joseph Prouse, Jordan Shaw and Shaq Taylor.
Rachel Chavkin, director of Hadestown, said: “This company is an extraordinary mix of artists – each is wholly unique, and brings a depth of soul and craft to the project.
“We’re thrilled to have back Amber Gray and Patrick Page, who have been with the show since the beginning, and Reeve Carney who did extraordinary work on the Canadian premiere.”
Hadestown, which is co-conceived by Ben T Matchstick, has set design by Rachel Hauck, costume by Michael Krass, lighting by Bradley King, sound by Nevin Steinberg and Jessica Paz and choreography by David Neumann.
It is produced in association with Mara Isaacs, Dale Franzen, Hunter Arnold and Tom Kirdahy.