Comedy Potted Sherlock is to play at the Vaudeville Theatre from December.
The show is written by Daniel Clarkson and Tom Clarkson, and stars Daniel Clarkson with Jefferson Turner and Lizzie Wort.
Potted Sherlock opens on December 8 and runs until January 11.
The production marks its London premiere and sees all 60 Sherlock stories told in 80 minutes.
It follows on from Potted Potter, which played in London, Edinburgh and New York.
Potted Sherlock is directed by Hanna Berrigan, designed by Simon Scullion and Louie Whitemore, and has lighting by Tim Mascall.
The sound is by Tom Lishman and the show is produced by James Seabright for Seabright Productions.